Siglecg^M5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Siglecg^M5Btlr
• Name: sialic acid binding Ig-like lectin G; mutation 5, Bruce Beutler
• MGI ID: MGI:6283658
• Synonyms: Chamonix
• Gene: Siglecg Location: Chr7:43057623-43067773 bp, + strand Genetic Position: Chr7, 28.25 cM
• Alliance: Siglecg^M5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 43,409,422 (v38) on chromosome 7, or base pair 1,230 in the GenBank genomic region NC_000073. The mutation corresponds to residue 743 in the mRNA sequence NM_172900 within exon 4 of 12 total exons. The mutation results in a serine to glycine substitution at position 200 (S200G) in the Siglec-G protein. (J:272022)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Siglecg Mutation: 41 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3834

References

• Original: J:272022 Zhong X, et al., Mutagenetix entry for Chamonix. MGI Direct Data Submission. 2019
• All: 1 reference(s)