Ftl1^tm1.1Ruvi
Targeted Allele Detail

Summary

• Symbol: Ftl1^tm1.1Ruvi
• Name: ferritin light polypeptide 1; targeted mutation 1.1, Ruben Vidal
• MGI ID: MGI:6115891
• Gene: Ftl1 Location: Chr7:45107368-45109308 bp, - strand Genetic Position: Chr7, 29.32 cM
• Alliance: Ftl1^tm1.1Ruvi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244236
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted upstream of exon 1 and a loxP site was inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed the neo cassette and exons 1 and 2. (J:244236)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ftl1 Mutation: 8 strains or lines available

References

• Original: J:244236 Li W, et al., Systemic and cerebral iron homeostasis in ferritin knock-out mice. PLoS One. 2015;10(1):e0117435
• All: 1 reference(s)