Tg(Igh-Lmp2a)ERlon
Transgene Detail

Summary

• Symbol: Tg(Igh-Lmp2a)ERlon
• Name: transgene insertion E, Richard Longnecker
• MGI ID: MGI:3769768
• Synonyms: TgE
• Transgene: Tg(Igh-Lmp2a)ERlon Location: unknown
• Alliance: Tg(Igh-Lmp2a)ERlon page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The Ig heavy chain promoter with Emu enhancer element was used to drive the expression of the Epstein-Barr virus latent membrane protein 2A. Expression was confirmed by in the spleen by immunoblot analysis and in the bone marrow cells by RT-PCR. (J:129571)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Two lines were created (E and 7).

References

• Original: J:129571 Caldwell RG, et al., Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity. 1998 Sep;9(3):405-11
• All: 9 reference(s)