Del(4D4Mit190-D4Mit51)2Aam
Targeted Allele Detail

Summary

• Symbol: Del(4D4Mit190-D4Mit51)2Aam
• Name: deletion, Chr 4, Alea A Mills 2; deletion, chr 4, Alea A Mills 2
• MGI ID: MGI:3714527
• Synonyms: Del1Aam, Del2Aam, Del(4D4Mit190-D4Mit51)1Aam
• Gene: Del(4D4Mit190-D4Mit51)2Aam Location: Chr4:150789308-155130473 bp Genetic Position: Chr4, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121726
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(4D4Mit190-D4Mit51)2Aam involves 95 genes/genome features (4930429L21Rik, Gm13113, Gm16334 ...) View all
• Mutation details: This deletion lacks the region on chromosome 4 including D4Mit190 through D4Mit51. This region is syntenic to human 1p36 and contains Chd5 as well as 51 other genes. (J:121726)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(4D4Mit190-D4Mit51)2Aam Mutation: 0 strains or lines available

References

• Original: J:121726 Bagchi A, et al., CHD5 is a tumor suppressor at human 1p36. Cell. 2007 Feb 9;128(3):459-75
• All: 2 reference(s)