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tlss
Spontaneous Allele Detail
Summary
Symbol: tlss
Name: thymo lympho sarcoma susceptibility
MGI ID: MGI:5438100
Gene: tlss  Location: unknown  
Alliance: tlss page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Spontaneous
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any tlss Mutation:  0 strains or lines available
Notes
Found in a stock homozygous for an ENU induced mutation at the haemoglobin beta complex (Hbb). The Hbb mutation arose from a treated 101/H male mated to a tester stock (PT) female. The sarcoma susceptibility trait itself may be due to an ENU induced recessive mutation; however tlss was first identified more than ten generations after the original Hbb mutant was produced. Probably spontaneous recessive mutation, but may be dominant with reduced penetrance.
References
Original:  J:169366 MouseBookTM, Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory