Kmt2e^tm1Nik
Targeted Allele Detail

Summary

• Symbol: Kmt2e^tm1Nik
• Name: lysine (K)-specific methyltransferase 2E; targeted mutation 1, Nigel Killeen
• MGI ID: MGI:3835592
• Gene: Kmt2e Location: Chr5:23639439-23709233 bp, + strand Genetic Position: Chr5, 10.33 cM, cytoband A3
• Alliance: Kmt2e^tm1Nik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145449
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An IRES-GFP element and a floxed neomycin resistance gene replaced exons 3 and 4. (J:145449)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kmt2e Mutation: 105 strains or lines available

References

• Original: J:145449 Zhang Y, et al., MLL5 contributes to hematopoietic stem cell fitness and homeostasis. Blood. 2009 Feb 12;113(7):1455-63
• All: 1 reference(s)