Krt33a^Plsh-3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Krt33a^Plsh-3Btlr
• Name: keratin 33A; polished 3 Bruce Beutler
• MGI ID: MGI:3834208
• Synonyms: Spikey
• Gene: Krt33a Location: Chr11:99902025-99907038 bp, - strand Genetic Position: Chr11, 63.35 cM, cytoband D
• Alliance: Krt33a^Plsh-3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, discovered by its visible phenotype among the G1 progeny of an ENU mutagenized male mouse, comprises a T to A transversion at position 1123 of the gene (Genbank: NM_027983), in the sixth of its seven exons. This results in replacement of isoleucine by asparagine at amino acid position 353 of the keratin protein (I353N), in a region involved in protein-protein interactions. (J:145290)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Krt33a Mutation: 30 strains or lines available

References

• Original: J:145290 Crozat K, et al., Record for "Spikey", updated 19th of February, 2009. MGI Direct Data Submission. 2009
• All: 1 reference(s)