Phenotypes associated with this allele

• Allele Symbol: Krt33a^Plsh-3Btlr
• Allele Name: polished 3 Bruce Beutler
• Allele ID: MGI:3834208
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Krt33a^Plsh-3Btlr/Krt33a^+	C57BL/6J-Krt33a^Plsh-3Btlr	MGI:3834211

Genotype
MGI:3834211

ht1

• Allelic Composition: Krt33a^Plsh-3Btlr/Krt33a⁺
• Genetic Background: C57BL/6J-Krt33a^Plsh-3Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:145290 )

N • mice with this mutation have a normal immune response to infection by Lysteria monocytogenes or by mouse cytomegalovirus (MCMV)

N • peritoneal macrophages from mutant mice produce tumor necrosis factor alpha at levels similar to those of wild-type macrophages in response to stimulation by ligands for the seven toll-like receptors (TLRs) included in the TLR Signaling Screen: TLR1/2, TLR2/6, TLR3, TLR4, TLR7 and TLR9

integument

disheveled coat ( J:145290 )

• the fur of mice heterozygous for this mutation appears unkempt, greasy, non-uniform and tufted or "spikey"

greasy coat ( J:145290 )

• the fur of mice heterozygous for this mutation appears unkempt, greasy, non-uniform and tufted or "spikey"