Tg(Lck-Socs3)1Kubo
Transgene Detail

Summary

• Symbol: Tg(Lck-Socs3)1Kubo
• Name: transgene insertion 1, Masato Kubo
• MGI ID: MGI:3783708
• Synonyms: SOCS3 Tg
• Transgene: Tg(Lck-Socs3)1Kubo Location: unknown
• Alliance: Tg(Lck-Socs3)1Kubo page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Socs3)1Kubo expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Socs3 (MGI:1201791)

• Mutation details: This transgene contains the Lck promoter with an Emu enhancer driving T-cell specific expression of a myc-tagged Socs3. Four identical lines were created and no line numbers were given. Expression of the myc-tagged transgene is 5 to 10 times higher than endogenous expression. (J:128797)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:128797 Matsumoto A, et al., A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production. J Exp Med. 2003 Feb 17;197(4):425-36
• All: 3 reference(s)