Fut4^tm1Jbl
Targeted Allele Detail

Summary

• Symbol: Fut4^tm1Jbl
• Name: fucosyltransferase 4; targeted mutation 1, John Lowe
• MGI ID: MGI:2387994
• Synonyms: FucT-IV^-
• Gene: Fut4 Location: Chr9:14659755-14663418 bp, - strand Genetic Position: Chr9, 4.3 cM
• Alliance: Fut4^tm1Jbl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79397
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 436 bp of genomic sequence encoding the catalytic domain was replaced with a neomycin selection cassette. (J:79397)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fut4 Mutation: 5 strains or lines available

References

• Original: J:79397 Homeister JW, et al., The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. Immunity. 2001 Jul;15(1):115-26
• All: 44 reference(s)