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Tg(Ins2-GP)#Psoh
Transgene Detail
Summary
Symbol: Tg(Ins2-GP)#Psoh
Name: transgene insertion, Pamela Ohashi
MGI ID: MGI:5568709
Synonyms: LCMV GP, RIP-gp
Transgene: Tg(Ins2-GP)#Psoh  Location: unknown  
Alliance: Tg(Ins2-GP)#Psoh page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe pancreas-specific rat insulin II promoter drives the expression of the lymphocytic choriomeningitis viral glycoprotein. Exons 2 and 3 of the beta-globin gene were ligated to the 3' end of the construct to provide splicing and polyadenylation signals. Immunohistochemistry confirmed protein expression in the pancreas. Two lines were established, Bln and Brx. However, the pound symbol (#) is used because the lines are pooled. (J:81285)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:81285 Ohashi PS, et al., Ablation of 'tolerance' and induction of diabetes by virus infection in viral antigen transgenic mice. Cell. 1991 Apr 19;65(2):305-17
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory