Trpm7^tm1Agry
Targeted Allele Detail

Summary

• Symbol: Trpm7^tm1Agry
• Name: transient receptor potential cation channel, subfamily M, member 7; targeted mutation 1, Alexey G Ryazanov
• MGI ID: MGI:5546500
• Synonyms: TRPm7^deltakinase
• Gene: Trpm7 Location: Chr2:126633485-126718150 bp, - strand Genetic Position: Chr2, 61.76 cM, cytoband F2
• Alliance: Trpm7^tm1Agry page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205665
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 32 through 36, encoding the kinase domain. (J:205665)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpm7 Mutation: 98 strains or lines available

References

• Original: J:205665 Ryazanova LV, et al., TRPM7 is essential for Mg(2+) homeostasis in mammals. Nat Commun. 2010;1:109
• All: 6 reference(s)