Tg(Lck-Fyn*Y528F)5525Cjg
Transgene Detail

Summary

• Symbol: Tg(Lck-Fyn*Y528F)5525Cjg
• Name: transgene insertion 5525, Cynthia J Guidos
• MGI ID: MGI:4360310
• Synonyms: TFF
• Transgene: Tg(Lck-Fyn*Y528F)5525Cjg Location: unknown
• Alliance: Tg(Lck-Fyn*Y528F)5525Cjg page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Fyn*Y528F)5525Cjg expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fyn (MGI:95602)

• Mutation details: The promoter drives T cell-specific expression of a mouse cDNA with nucleotide substitutions that result in the amino acid substitution of phenylalanine for tyrosine at position 528 (Y528F). Line 5525 was generated. (J:37062)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:37062 Groves T, et al., Fyn can partially substitute for Lck in T lymphocyte development. Immunity. 1996 Nov;5(5):417-28
• All: 1 reference(s)