b2b2696.2Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b2696.2Clo
• Name: Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
• MGI ID: MGI:5620188
• Gene: b2b2696.2Clo Location: unknown
• Alliance: b2b2696.2Clo page

Mutant exhibits a right aortic arch which was confirmed by ECM imaging.

Show the 11 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b2696Clo.

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any b2b2696.2Clo Mutation: 0 strains or lines available

Notes

General Notes (Mutant 2): Summative Diagnosis:
Cardiovascular phenotypes: Atrioventricular septal defect (AVSD), left ventricular hypertrophy, right sided aortic arch, vascular ring and other aortic arch anomalies

Noncardiovascular phenotype: Craniofacial defects including micrognathia, midline facial cleft, bilateral anopthalmia, low set ears, hypoplastic thymus, renal anomalies including duplex kidneys and hydroureter

Phenotypic Similarity to Human Syndrome:
DiGeorge syndrome

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)