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Hoxa3tm1Mrc
Targeted Allele Detail
Summary
Symbol: Hoxa3tm1Mrc
Name: homeobox A3; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:1857992
Synonyms: hox-1.5-, Hoxa3-
Gene: Hoxa3  Location: Chr6:52146042-52190316 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance: Hoxa3tm1Mrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:17753
Parent Cell Line:  CC1.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance gene was inserted into sequences encoding the homeobox domain. (J:17753)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 101 assay results
In Structures Affected by this Mutation: 36 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa3 Mutation:  24 strains or lines available
References
Original:  J:17753 Chisaka O, et al., Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5 [see comments]. Nature. 1991 Apr 11;350(6318):473-9
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory