Hrh1^Bphs-s
Spontaneous Allele Detail

Summary

• Symbol: Hrh1^Bphs-s
• Name: histamine receptor H1; B pertussis induced histamine sensitization, susceptible
• MGI ID: MGI:2182953
• Synonyms: Bphs^s
• Gene: Hrh1 Location: Chr6:114374897-114459432 bp, + strand Genetic Position: Chr6, 53.05 cM
• Alliance: Hrh1^Bphs-s page

Mutation origin

• Strain of Origin: various inbred strains

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: This allele confers susceptibility to Bordetella pertussis induced histamine sensitization and occurs in most strains including SJL/J. (J:77938)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hrh1 Mutation: 35 strains or lines available

Notes

CFW, SJL, and SWR replaced by "various inbred strains" as list of susceptible strains increased via J:77938. llw2 1/21/15

References

• Original: J:4933 Sudweeks JD, et al., Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3700-4
• All: 4 reference(s)