Abcg2^tm1.1Ssf
Targeted Allele Detail

Summary

• Symbol: Abcg2^tm1.1Ssf
• Name: ATP binding cassette subfamily G member 2 (Junior blood group); targeted mutation 1.1, Silvia Santamarina-Fojo
• MGI ID: MGI:5506750
• Gene: Abcg2 Location: Chr6:58561476-58669436 bp, + strand
• Alliance: Abcg2^tm1.1Ssf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165703
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The floxed region containing exon 2, which contains the translation initiation codon, and some of the flanking intronic sequence was excised via cre-mediated recombination. An aberrant (smaller than wild-type) ABCG2 transcript, but no ABCG2 protein, is detected. (J:165703)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abcg2 Mutation: 74 strains or lines available

References

• Original: J:165703 Santamarina-Fojo S, et al., Generation of a conditional Abcg2 allele. MGI Direct Data Submission. 2006
• All: 2 reference(s)