Mfsd2atm1Dls
Targeted Allele Detail
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Symbol: |
Mfsd2atm1Dls |
Name: |
MFSD2 lysolipid transporter A, lysophospholipid; targeted mutation 1, David L Silver |
MGI ID: |
MGI:5474960 |
Gene: |
Mfsd2a Location: Chr4:122840643-122854981 bp, - strand Genetic Position: Chr4, 57.34 cM, cytoband D1
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Alliance: |
Mfsd2atm1Dls page
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Decreased liver triglycerides in Mfsd2atm1Dls/Mfsd2atm1Dls mice
Show the 7 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:194781
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neo cassette replaced the sequence spanning part of exon 4 through exon 13. Western blot analysis confirmed the absence of protein expression in the cortex, cerebellum, hypothalamus and brain stem.
(J:194781)
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Generation of the Mfsd2atm1Dls allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mfsd2a Mutation: |
36 strains or lines available
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Original: |
J:194781 Berger JH, et al., Major facilitator superfamily domain-containing protein 2a (MFSD2A) has roles in body growth, motor function, and lipid metabolism. PLoS One. 2012;7(11):e50629 |
All: |
6 reference(s) |
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