F2rl1^tm1Jkaw
Targeted Allele Detail

Summary

• Symbol: F2rl1^tm1Jkaw
• Name: F2R like trypsin receptor 1; targeted mutation 1, Junichi Kawagoe
• MGI ID: MGI:3620551
• Synonyms: Par2^-
• Gene: F2rl1 Location: Chr13:95648240-95661735 bp, - strand Genetic Position: Chr13, 49.53 cM
• Alliance: F2rl1^tm1Jkaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106127
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An IRES-beta-gal-neo cassette replaced most of the coding sequence in exon 2. (J:106127)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any F2rl1 Mutation: 58 strains or lines available

References

• Original: J:106127 Kawagoe J, et al., Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Jpn J Pharmacol. 2002 Jan;88(1):77-84
• All: 2 reference(s)