Cacnb4^lh
Spontaneous Allele Detail

Summary

• Symbol: Cacnb4^lh
• Name: calcium channel, voltage-dependent, beta 4 subunit; lethargic
• MGI ID: MGI:1856936
• Synonyms: beta4^lh, lh
• Gene: Cacnb4 Location: Chr2:52318332-52566816 bp, - strand Genetic Position: Chr2, 29.98 cM
• Alliance: Cacnb4^lh page

Mutation origin

• Strain of Origin: BALB/cGn

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: A four bp insertion that disrupts the consensus 5' splice site of intron A/B was identified. Reduced levels of transcripts are produced from this allele and are present at approximately 20% of the normal levels in homozygous mice. (J:38214)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacnb4 Mutation: 32 strains or lines available

References

• Original: J:28465 Dickie MM, Lethargic (lh). Mouse News Lett. 1964;30:31
• All: 34 reference(s)