Tg(Ins2-Iapp)6Soel
Transgene Detail

Summary

• Symbol: Tg(Ins2-Iapp)6Soel
• Name: transgene insertion 6, Walter C Soeller
• MGI ID: MGI:3771295
• Synonyms: r-TG, Tg(Iapp)6Wcs, Tg(Ins2-Iapp)6Soll
• Transgene: Tg(Ins2-Iapp)6Soel Location: unknown
• Alliance: Tg(Ins2-Iapp)6Soel page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins2-Iapp)6Soel expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Iapp (MGI:96382)

• Tg(Ins2-Iapp)6Soel expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• The rat insulin 2 promoter drives expression of mouse Iapp in islet cells. (J:130022)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:130022 Huang CJ, et al., Induction of endoplasmic reticulum stress-induced -cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1656-62
• All: 7 reference(s)