P2ry6^tm1Jabo
Targeted Allele Detail

Summary

• Symbol: P2ry6^tm1Jabo
• Name: pyrimidinergic receptor P2Y, G-protein coupled, 6; targeted mutation 1, Joshua A Boyce
• MGI ID: MGI:5304911
• Synonyms: p2ry6^flox
• Gene: P2ry6 Location: Chr7:100586837-100623856 bp, - strand Genetic Position: Chr7, 54.46 cM
• Alliance: P2ry6^tm1Jabo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179177
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. A floxed neo cassette was inserted downstream of exon 3. (J:179177)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any P2ry6 Mutation: 17 strains or lines available

References

• Original: J:179177 Giannattasio G, et al., The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation. J Immunol. 2011 Aug 1;187(3):1486-95
• All: 2 reference(s)