Clec4d^tm1.1Shoy
Targeted Allele Detail

Summary

• Symbol: Clec4d^tm1.1Shoy
• Name: C-type lectin domain family 4, member d; targeted mutation 1.1, Sho Yamasaki
• MGI ID: MGI:5528858
• Gene: Clec4d Location: Chr6:123239070-123252224 bp, + strand Genetic Position: Chr6, 58.33 cM, cytoband F3
• Alliance: Clec4d^tm1.1Shoy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203159
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed hygromycin resistance cassette replaced exons 1 and 2. Cre-mediated recombination removed the hygromycin resistance cassette. Western blot analysis confirmed the absence of protein expression. (J:203159)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec4d Mutation: 26 strains or lines available

References

• Original: J:203159 Miyake Y, et al., C-type lectin MCL is an FcRgamma-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor. Immunity. 2013 May 23;38(5):1050-62
• All: 2 reference(s)