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Chemically induced Allele Detail
Symbol: Ebf1M4Btlr
Name: early B cell factor 1; mutation 4, Bruce Beutler
MGI ID: MGI:6268783
Synonyms: Catastrophic
Gene: Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance: Ebf1M4Btlr page
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
Mutation detailsENU-induced T to A transversion at base pair 44,883,885 (v38) on chromosome 11, or base pair 265,786 in the GenBank genomic region NC_000077. The mutation corresponds to residue 787 in the mRNA sequence NM_001290709 within exon 8 of 16 total exons. The mutation results in an asparagine to lysine substitution at position 236 (N236K) in the EBF1 protein. (J:267560)
Inheritance:    Dominant
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:  73 strains or lines available
Original:  J:267560 Choi JH, et al., Mutagenetix entry for Catastrophic. MGI Direct Data Submission. 2018;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.13
The Jackson Laboratory