Dock2^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dock2^m5Btlr
• Name: dedicator of cyto-kinesis 2; mutation 5, Bruce Beutler
• MGI ID: MGI:5695264
• Synonyms: Arches
• Gene: Dock2 Location: Chr11:34176815-34674719 bp, - strand Genetic Position: Chr11, 19.68 cM, cytoband A5
• Alliance: Dock2^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 34,689,760 (v38) on chromosome 11, or base pair 94,146 in the GenBank genomic region NC_000077. The mutation corresponds to residue 2,064 in the mRNA sequence NM_033374 within exon 20 of 52 total exons. The mutation results in a methionine (M) to lysine (K) substitution at position 661 (M661K). (J:225938)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock2 Mutation: 142 strains or lines available

References

• Original: J:225938 Zeng M, et al., Mutagenetix entry for Arches. MGI Direct Data Submission. 2015
• All: 1 reference(s)