Limk2^whe
Spontaneous Allele Detail

Summary

• Symbol: Limk2^whe
• Name: LIM domain kinase 2; white eyes
• MGI ID: MGI:3612836
• Gene: Limk2 Location: Chr11:3294256-3359189 bp, - strand Genetic Position: Chr11, 2.34 cM
• Alliance: Limk2^whe page

Mutation origin

• Strain of Origin: B6.Cg-Lep^ob/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A spontaneous mutation results in a C-to-A point mutation in the first base of intron 12. This eliminates the exon 12 splice donor site by changing it from G-GT to G-TT.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Limk2 Mutation: 74 strains or lines available

References

• Original: J:127016 Giggey J, et al., A new spontaneous mutation causing corneal opacity. MGI Direct Data Submission. 2007
• All: 2 reference(s)