Tmem102^tm1.1Jyen
Targeted Allele Detail

Summary

• Symbol: Tmem102^tm1.1Jyen
• Name: transmembrane protein 102; targeted mutation 1.1, Jeffrey Yen
• MGI ID: MGI:6274402
• Synonyms: CBAP^-
• Gene: Tmem102 Location: Chr11:69694429-69696450 bp, - strand Genetic Position: Chr11, 42.88 cM
• Alliance: Tmem102^tm1.1Jyen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200103
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Both coding exons were replaced with a lacZ gene and loxP site flanked neomycin resistance gene cassette. The neo cassette was removed by subsequent Cre-mediated recombination. The resulting homozygous mutant mice lacked expression of both the encoded mRNA and protein in liver. (J:200103)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem102 Mutation: 20 strains or lines available

References

• Original: J:200103 Chiang YJ, et al., CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-Cell adhesion and migration. PLoS One. 2013;8(4):e61761
• All: 1 reference(s)