Helb^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Helb^{tm1(KOMP)Vlcg}
• Name: helicase (DNA) B; targeted mutation 1, Velocigene
• MGI ID: MGI:4881306
• Gene: Helb Location: Chr10:119919513-119948892 bp, - strand Genetic Position: Chr10, 67.94 cM
• Alliance: Helb^{tm1(KOMP)Vlcg} page
• IMPC: Helb gene page

Mutation origin

• Mutant Cell Lines: 15578A-A5, 15578A-B4, 15578A-C11, 15578A-C12, 15578A-D4, 15578A-E12
• Germline Transmission: Earliest citation of germline transmission: J:231089
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 28189 bp between positions 119920576-119948764 of Chromosome 10 (Build GRCm39). Immunoblots show absence of protein expression from this allele. (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Helb Mutation: 67 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)