Ppp3cb^M3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ppp3cb^M3Btlr
• Name: protein phosphatase 3, catalytic subunit, beta isoform; mutation 3, Bruce Beutler
• MGI ID: MGI:6113566
• Synonyms: Eden_express
• Gene: Ppp3cb Location: Chr14:20549432-20596641 bp, - strand Genetic Position: Chr14, 11.53 cM, cytoband B
• Alliance: Ppp3cb^M3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 20,528,195 (v38) on chromosome 14, or base pair 18,379 in the GenBank genomic region NC_000080. The mutation corresponds to residue 619 in the mRNA sequence NM_008914 within exon 4 of 14 total exons. The mutation results in substitution of cysteine 162 for a premature stop codon (C162*) in the encoded protein. (J:254889)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp3cb Mutation: 66 strains or lines available

References

• Original: J:254889 Zhong X, et al., Mutagenetix entry for Eden_express. MGI Direct Data Submission. 2018
• All: 1 reference(s)