Ces1c^{em1(IMPC)Ccpcz}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ces1c^{em1(IMPC)Ccpcz}
• Name: carboxylesterase 1C; endonuclease-mediated mutation 1, Institute of Molecular Genetics
• MGI ID: MGI:7425578
• Gene: Ces1c Location: Chr8:93825643-93857911 bp, - strand Genetic Position: Chr8, 44.99 cM
• Alliance: Ces1c^{em1(IMPC)Ccpcz} page
• IMPC: Ces1c gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Czech Centre for Phenogenomics using Cas9 and guides with spacer sequences CACTGTAGAATCTGACATGA and TGCAAGGTTAATGTGGCCAT that targeted exon(s) ENSMUSE00001217584.2 ENSMUSE00001265349.2 ENSMUSE00001282845.2 ENSMUSE00001390126.2 ENSMUSE00001390361.2 ENSMUSE00001391794.2 ENSMUSE00001391853.2 ENSMUSE00001393162.2 ENSMUSE00001393382.2 ENSMUSE00001719947.1 ENSMUSE00001719948.1 ENSMUSE00001719950.1 ENSMUSE00001719951.1. This resulted in deletion(s) of 13 bp (location: Chr8:93876723-93876735; GRCm39), 1045 bp (location: Chr8:93850729-93851773; GRCm39), and 24543 bp (location: Chr8:93852157-93876699; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ces1c Mutation: 38 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)