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Transgene Detail
Symbol: Tg(KRT14-Il18)#Knak
Name: transgene insertion, Kenji Nakanishi
MGI ID: MGI:2388817
Synonyms: KIL-18Tg
Transgene: Tg(KRT14-Il18)#Knak  Location: unknown  
Alliance: Tg(KRT14-Il18)#Knak page
Strain of Origin:  C57BL/6
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(KRT14-Il18)#Knak expresses 1 gene
Mutation detailsThe transgenic construct consisted of an Il18 cDNA fragment was adjoined to a human keratin 14 promoter region and rabbit beta-globin intron. The human keratin 14 promoter drives expression in epidermal tissue. Northern blot analysis of showed expression of the construct in the skin, but not in liver, kidney, colon, lung,brain, or spleen. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:78602)
View phenotypes and curated references for all genotypes (concatenated display).
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:78602 Konishi H, et al., IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11340-5
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory