Tg(Tek-cre)1Xyfu
Transgene Detail

Summary

• Symbol: Tg(Tek-cre)1Xyfu
• Name: transgene insertion 1, Xin-Yuan Fu
• MGI ID: MGI:2683222
• Synonyms: TIE2e-Cre
• Transgene: Tg(Tek-cre)1Xyfu Location: unknown
• Alliance: Tg(Tek-cre)1Xyfu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tek-cre)1Xyfu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Tek

• Mutation details: The Tek promoter drove expression of cre recombinase in the endothelium of the brain, heart, liver, and other tissues. Expression was detected in 1.5% of bone marrow cells. The authors concluded that expression is restricted to endothelium with minimal leakage. (J:86655)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tek (species not specified) Summary of all recombinase alleles driven by Tek.

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:86655 Kano A, et al., Endothelial cells require STAT3 for protection against endotoxin-induced inflammation. J Exp Med. 2003 Nov 17;198(10):1517-25
• All: 10 reference(s)