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Tg(Thy1-cre)1Vln
Transgene Detail
Summary
Symbol: Tg(Thy1-cre)1Vln
Name: transgene insertion 1, Fred Van Leuven
MGI ID: MGI:2684620
Synonyms: thy1-Cre
Transgene: Tg(Thy1-cre)1Vln  Location: unknown  
Alliance: Tg(Thy1-cre)1Vln page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Thy1-cre)1Vln expression driven by 1 gene
 
Mutation detailsSequence encoding cre recombinase was adjoined to the mouse Thy1 promoter. Expression was driven in neurons of the postnatal cortex and hippocampus. (J:87229)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Thy1 (mouse)
Summary of all recombinase alleles driven by Thy1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 4 assay results
2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:87229 Dewachter I, et al., Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice. J Neurosci. 2002 May 1;22(9):3445-53
All:  47 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory