Havcr2^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Havcr2^tm1Vlcg
• Name: hepatitis A virus cellular receptor 2; targeted mutation 1, Velocigene
• MGI ID: MGI:5617473
• Gene: Havcr2 Location: Chr11:46345762-46372082 bp, + strand Genetic Position: Chr11, 27.9 cM
• Alliance: Havcr2^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209885
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Insertion of a vector containing a neo cassette disrupts expression of the gene. (J:209885)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Havcr2 Mutation: 32 strains or lines available

References

• Original: J:209885 Gorman JV, et al., Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection. J Immunol. 2014 Apr 1;192(7):3133-42
• All: 3 reference(s)