Gpr183^tm1.1Cys
Targeted Allele Detail

Summary

• Symbol: Gpr183^tm1.1Cys
• Name: G protein-coupled receptor 183; targeted mutation 1.1, Jason G Cyster
• MGI ID: MGI:4399081
• Synonyms: Ebi2^GFP
• Gene: Gpr183 Location: Chr14:122189963-122202607 bp, - strand Genetic Position: Chr14, 65.86 cM
• Alliance: Gpr183^tm1.1Cys page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151077
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with EGFP and a floxed neo cassette. Germ line, cre mediated recombination removes the neo cassette. The reduction in transcript expression was confirmed by quantitative PCR on immune cell population extracts from heterozygous mice. (J:151077)

Expression

In Mice Carrying this Mutation:

18 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr183 Mutation: 23 strains or lines available

References

• Original: J:151077 Pereira JP, et al., EBI2 mediates B cell segregation between the outer and centre follicle. Nature. 2009 Aug 27;460(7259):1122-6
• All: 22 reference(s)