Vsig4^tm1Gne
Targeted Allele Detail

Summary

• Symbol: Vsig4^tm1Gne
• Name: V-set and immunoglobulin domain containing 4; targeted mutation 1, Genentech
• MGI ID: MGI:3806036
• Synonyms: CRIg^-, CRIg ko
• Gene: Vsig4 Location: ChrX:95290809-95337044 bp, - strand Genetic Position: ChrX, 42.69 cM
• Alliance: Vsig4^tm1Gne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138691
• Parent Cell Line: C2 (Nagy) (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced with a neo cassette. (J:138691)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsig4 Mutation: 9 strains or lines available

References

• Original: J:138691 Helmy KY, et al., CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell. 2006 Mar 10;124(5):915-27
• All: 13 reference(s)