Tg(CD46)373Zbz
Transgene Detail

Summary

• Symbol: Tg(CD46)373Zbz
• Name: transgene insertion 373, Universitatsspital Zurich, Biologisches Zentrallaboratorium
• MGI ID: MGI:6501992
• Synonyms: CD46Ge, TgN(hCD46Ge)373Zbz
• Transgene: Tg(CD46)373Zbz Location: unknown
• Alliance: Tg(CD46)373Zbz page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H/He)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD46)373Zbz expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD46 (4179)

  Cd46	(MGI:1203290)

• Mutation details: The transgene comprises a 400-kb yeast artificial chromosome (YAC) RCA1 that contains the human 50-kb CD46 gene and the preceding CR1-like and MCP-like genetic elements. (J:160878)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:160878 Mrkic B, et al., Measles virus spread and pathogenesis in genetically modified mice. J Virol. 1998 Sep;72(9):7420-7
• All: 13 reference(s)