Sppl2a^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Sppl2a^m1Btlr
• Name: signal peptide peptidase like 2A; mutation 1, Bruce Beutler
• MGI ID: MGI:5806432
• Synonyms: abra
• Gene: Sppl2a Location: Chr2:126732311-126775155 bp, - strand Genetic Position: Chr2, 61.76 cM, cytoband F3
• Alliance: Sppl2a^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 126,923,594 (v38) on chromosome 2, or base pair 9,669 in the GenBank genomic region NC_000068 encoding the gene. The mutation corresponds to residue 830 in the mRNA sequence NM_023220 within exon 6 of 15 total exons. The mutation results in a serine (S) to proline (P) substitution at position 203 (S203P) in the protein. (J:236687)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sppl2a Mutation: 45 strains or lines available

References

• Original: J:236687 Wang K-W, et al., Mutagenetix entry for abra. MGI Direct Data Submission. 2016
• All: 1 reference(s)