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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sppl2am1Btlr
mutation 1, Bruce Beutler
MGI:5806432
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sppl2am1Btlr/Sppl2am1Btlr C57BL/6J-Sppl2am1Btlr MGI:5807184


Genotype
MGI:5807184
hm1
Allelic
Composition		 Sppl2am1Btlr/Sppl2am1Btlr
Genetic
Background		 C57BL/6J-Sppl2am1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sppl2am1Btlr mutation (0 available); any Sppl2a mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased IgG level ( J:236687 )
• mice show reduced T-dependent antibody responses to ovalbumin administered with aluminum hydroxide

immune system
decreased IgG level ( J:236687 )
• mice show reduced T-dependent antibody responses to ovalbumin administered with aluminum hydroxide




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory