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Targeted Allele Detail
Symbol: Hivep3tm1Glm
Name: human immunodeficiency virus type I enhancer binding protein 3; targeted mutation 1, Laurie H Glimcher
MGI ID: MGI:3586993
Synonyms: KRC-, Shn3-
Gene: Hivep3  Location: Chr4:119590982-119992608 bp, + strand  Genetic Position: Chr4, 55.51 cM, cytoband D1
Alliance: Hivep3tm1Glm page
Trabecular bone and clavicle analysis in various mice with Runx2tm1Mjo and/or Hivep3tm1Glm alleles

Show the 4 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:100058
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA vector was constructed to replace all of exon 4 with a neomycin resistance cassette. Mutants were shown to lack protein. (J:100058)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hivep3 Mutation:  63 strains or lines available
Original:  J:100058 Oukka M, et al., Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. J Exp Med. 2004 Jan 5;199(1):15-24
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory