Ccr10^tm1.1Nax
Targeted Allele Detail

Summary

• Symbol: Ccr10^tm1.1Nax
• Name: C-C motif chemokine receptor 10; targeted mutation 1.1, Na Xiong
• MGI ID: MGI:4837004
• Gene: Ccr10 Location: Chr11:101063824-101066269 bp, - strand Genetic Position: Chr11, 64.34 cM
• Alliance: Ccr10^tm1.1Nax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:165323
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.7 kb DNA fragment encoding the N-terminal extracellular domain and all 7 transmembrane domains was replaced by EGFP and a floxed neomycin selection cassette. The selection cassette was subsequently removed by cre mediated excision. (J:165323)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr10 Mutation: 13 strains or lines available

References

• Original: J:165323 Jin Y, et al., CCR10 is important for the development of skin-specific gammadeltaT cells by regulating their migration and location. J Immunol. 2010 Nov 15;185(10):5723-31
• All: 6 reference(s)