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Radiation induced Allele Detail
Symbol: Foxq1sa
Name: forkhead box Q1; satin
MGI ID: MGI:1857026
Synonyms: sa, satin
Gene: Foxq1  Location: Chr13:31742153-31744959 bp, + strand  Genetic Position: Chr13, 13.46 cM
Alliance: Foxq1sa page
Strain of Origin:  (101/Rl x C3H/Rl)F1
Allele Type:    Radiation induced
Mutation:    Intragenic deletion
Mutation detailsThis allele occurred in descendants of a gamma irradiation experiment. The underlying mutation was identified as a 67 bp intragenic deletion. The deletion causes a frame shift resulting in a truncated 376 amino acid protein but does not affect the first 228 residues, including the characteristic WH DNA-binding domain. The mutant protein is predicted to bind to its DNA targets but fails at transcriptional activation or repression because the specific C-terminal domains are missing. (J:75422)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 16 strains available      Cell Lines: 0 lines available
Carrying any Foxq1 Mutation:  24 strains or lines available
Original:  J:99457 Major MH, Satin, sa. Mouse News Lett. 1955;12:47
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory