Mtus1^{Gt(RRA048)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Mtus1^{Gt(RRA048)Byg}
• Name: mitochondrial tumor suppressor 1; gene trap RRA048, BayGenomics
• MGI ID: MGI:4126369
• Gene: Mtus1 Location: Chr8:41443951-41586763 bp, - strand Genetic Position: Chr8, 23.89 cM
• Alliance: Mtus1^{Gt(RRA048)Byg} page

Mutation origin

• Mutant Cell Line: RRA048
• Germline Transmission: Earliest citation of germline transmission: J:212144
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The beta-geo gene trap was inserted between exon 9 and 10. Western blot analysis confirmed the absence of protein expression in the heart. (J:212144)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRA048	CC183580 ; (MGI Seq Detail)	5' RACE	Chr8:41468426-41475633 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  50 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	213 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtus1 Mutation: 123 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)