Nectin4^em1Jaa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nectin4^em1Jaa
• Name: nectin cell adhesion molecule 4; endonuclease-mediated mutation 1, An-Soo Jang
• MGI ID: MGI:8213563
• Gene: Nectin4 Location: Chr1:171197741-171215855 bp, + strand Genetic Position: Chr1, 79.37 cM, cytoband H2
• Alliance: Nectin4^em1Jaa page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination using guide RNAs created a deletion of exon 2 and 7 sequences. (J:336809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nectin4 Mutation: 36 strains or lines available

References

• Original: J:336809 Lee PH, et al., Nectin4 is a potential therapeutic target for asthma. Front Immunol. 2022;13:1049900
• All: 1 reference(s)