Ppp3cb^M6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ppp3cb^M6Btlr
• Name: protein phosphatase 3, catalytic subunit, beta isoform; mutation 6, Bruce Beutler
• MGI ID: MGI:6286032
• Synonyms: Havana
• Gene: Ppp3cb Location: Chr14:20549432-20596641 bp, - strand Genetic Position: Chr14, 11.53 cM, cytoband B
• Alliance: Ppp3cb^M6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 20,531,752 (v38) on chromosome 14, or base pair 14,822 in the GenBank genomic region NC_000080 encoding Ppp3cb. The mutation corresponds to residue 327 in the mRNA sequence NM_008914 within exon 2 of 14 total exons. The mutation results in a valine to alanine substitution at position 65 (V65A) in the CnAbeta protein. (J:272840)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp3cb Mutation: 66 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3809

References

• Original: J:272840 Zhong X, et al., Mutagenetix entry for Havana. MGI Direct Data Submission. 2019
• All: 1 reference(s)