All Phenotypes Ppp3cb<M6Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ppp3cb^M6Btlr
mutation 6, Bruce Beutler
MGI:6286032

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ppp3cb^M6Btlr/Ppp3cb^M6Btlr	C57BL/6J-Ppp3cb^M6Btlr	MGI:6286034

Allelic Composition	Ppp3cb^M6Btlr/Ppp3cb^M6Btlr
Genetic Background	C57BL/6J-Ppp3cb^M6Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp3cb^M6Btlr mutation (0 available); any Ppp3cb mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal lymphocyte morphology ( J:272840 )

• increase in the B to T cell ratio in the peripheral blood

• reduced frequencies of T cells in the peripheral blood

• reduced frequencies of CD4+ T cells in the peripheral blood

• reduced frequencies of CD8+ T cells in the peripheral blood

hematopoietic system

abnormal lymphocyte morphology ( J:272840 )

• increase in the B to T cell ratio in the peripheral blood

• reduced frequencies of T cells in the peripheral blood

• reduced frequencies of CD4+ T cells in the peripheral blood

• reduced frequencies of CD8+ T cells in the peripheral blood

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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