C3H101H-Col3a1<Tsk2>/H Strain Detail MGI Mouse MGI:3579305

C3H101H-Col3a1^Tsk2/H Strain Detail

Summary

1 associated mutation

Mutation Carried	Marker
Col3a1^Tsk2	Col3a1

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
systemic scleroderma	√

Key

√

disease model

expected model not found

2 associated strain records at IMSR

IMSR	Repository	IMSR Strain	Why Matched
EM:02195	EMMA	C3H101H-Col3a1^Tsk2/H	exact match to ID
HAR:67	HAR	C3H101H-Col3a1^Tsk2/H	exact match to name

Earliest

J:215227 Long KB, et al., The Tsk2/+ mouse fibrotic phenotype is due to a gain-of-function mutation in the PIIINP segment of the Col3a1 gene. J Invest Dermatol. 2014 Oct 20;
All

1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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