Runx1^tm3Itan
Targeted Allele Detail

Summary

• Symbol: Runx1^tm3Itan
• Name: runt related transcription factor 1; targeted mutation 3, Ichiro Taniuchi
• MGI ID: MGI:4458865
• Synonyms: Runx1^P1N
• Gene: Runx1 Location: Chr16:92398354-92622962 bp, - strand Genetic Position: Chr16, 53.7 cM
• Alliance: Runx1^tm3Itan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160791
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• The distal P1 promoter region and exon 1 were replaced with a neo cassette. (J:160791)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx1 Mutation: 35 strains or lines available

References

• Original: J:160791 Bee T, et al., Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis. Blood. 2010 Apr 15;115(15):3042-50
• All: 5 reference(s)