About   Help   FAQ
Cfc1tm1Mms
Targeted Allele Detail
Summary
Symbol: Cfc1tm1Mms
Name: cryptic, EGF-CFC family member 1; targeted mutation 1, Michael M Shen
MGI ID: MGI:2179530
Synonyms: Cryptic
Gene: Cfc1  Location: Chr1:34574729-34583392 bp, + strand  Genetic Position: Chr1, 13.34 cM, cytoband B
Alliance: Cfc1tm1Mms page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58104
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 3 and all of exons 4 and 5 were replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant E7.5 embryos were identified by PCR analysis. (J:58104)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cfc1 Mutation:  22 strains or lines available
References
Original:  J:58104 Yan YT, et al., Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes Dev. 1999 Oct 1;13(19):2527-37
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory