Supv3l1tm2.1Jkl
Targeted Allele Detail
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Symbol: |
Supv3l1tm2.1Jkl |
Name: |
suppressor of var1, 3-like 1 (S. cerevisiae); targeted mutation 2.1, Jan Klysik |
MGI ID: |
MGI:3833741 |
Synonyms: |
Supv3L1tm3Jkl |
Gene: |
Supv3l1 Location: Chr10:62264988-62285517 bp, - strand Genetic Position: Chr10, 32.4 cM
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Alliance: |
Supv3l1tm2.1Jkl page
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Thymic atrophy in Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl Tg(CAG-cre/Esr1*)5Amc/0 mice
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:144991
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Germ line, flp mediated recombination was used to remove the neo cassette leaving exon 14 floxed. (J:144991)
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Targeting the Supv3l1 allele to generate the Supv3l1tm2Jkl, Supv3l1tm2.1Jkl, Supv3l1tm2.2Jkl, and Supv3l1tm2.3Jkl alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Supv3l1 Mutation: |
42 strains or lines available
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Original: |
J:144991 Paul E, et al., Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mamm Genome. 2009 Feb;20(2):92-108 |
All: |
1 reference(s) |
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